Covid vaccine rewrites DNA?
Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line
Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection. Furthermore, a recent study showed that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of human...www.mdpi.com
@egg_
Hm. OK, so the "normal" run of events in cells is DNA is transcribed (copied) into RNA (to get used "translated" in protein creation). Reverse transcription is this in reverse, ie RNA getting transcribed to DNA.
I guess these guys are picking up another group's work which demonstrated that you can deliver SARS-COV2 RNA into humans and that RNA can be transcribed to DNA and then actually integrated into the genomic DNA (ie the original DNA of the human).
That's the real story, that's surprising. I guess I didn't know this was the case, but I'm not following covid stuff in work.
All this paper has done is extended that work such that the region they integrated that DNA back into was liver. So you end up with sars DNA in and around liver DNA. I don't know much about livers other than they are pretty active from the perspective of cell creation, and I guess if you want to have something integrated into a genome, you want it to be integrated into a part of the genome that's actively being used ("expressed").
So basically I suppose they're saying (didn't read past the abstract) is they can present covid RNA to the host (human), and they can design this RNA such that it gets integrated into genomic DNA in the region that codes for liver. The idea being that the DNA is then transcribed back into RNA, then translated to protein. At that point the body magically knows this is on the naughty protein list, and mounts an adaptive immune response to that. In effect the body is generating its own vaccine.
I think.
